selective peripheral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0957	Isradipine	PN 200-110	Calcium Channel , Autophagy
	Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc...		Calcium Channel , Autophagy
T16411	Otenzepad	AF-DX 116	AChR
	Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.		AChR
T21447	Tolazoline	Priscol,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin	Adrenergic Receptor
	Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse th...		Adrenergic Receptor
T10244	ACY-1083		HDAC
	ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.		HDAC
T0806	Flunarizine dihydrochloride	Flunarizine 2HCl,KW-3149,R14950	Calcium Channel , Dopamine Receptor , Sodium Channel
	Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihydrochloride (R14950) is effective in the prophylaxis of mig...		Calcium Channel , Dopamine Receptor , Sodium Channel
T5385	Radiprodil	RGH-896	NMDAR , iGluR
	Radiprodil (RGH-896) (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP).		NMDAR , iGluR
T2371	Emapunil	AC-5216,XBD-173	Others
	Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.		Others
T10998	Deriglidole	SL 86-0715	Adrenergic Receptor
	Deriglidole (SL 86-0715) is a peripheral adrenergic receptor antagonist that is a selective inhibitor of alpha2 receptors. Deriglidole inhibits colistin and Idazoxan but does not show activity against prazosin and rat co...		Adrenergic Receptor
T10073	2-Iodomelatonin		Melatonin Receptor
	2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin bind...		Melatonin Receptor
TP1918L1	Lys-[Des-Arg9]Bradykinin acetate	Lys-[Des-Arg9]Bradykinin acetate (71800-36-7 free base)	Bradykinin Receptor
	Lys-[Des-Arg9]Bradykinin acetate is an endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces p...		Bradykinin Receptor
TP1918L	Lys-[Des-Arg9]Bradykinin,TFA	Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)	Bradykinin Receptor
	Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripher...		Bradykinin Receptor
T13664	DSP-4 hydrochloride	Neurotoxin DSP 4 (hydrochloride)	Others
	DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus...		Others
TN2322	Yangambin		Calcium Channel , PAFR
	Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...		Calcium Channel , PAFR
T2525	Alosetron hydrochloride	Lotronex,GR 68755C,GR 68755,GR 68755X	5-HT Receptor
	Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system,...		5-HT Receptor
T1050	Prazosin hydrochloride	Prazosin hydrochloride,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,Minipress	Potassium Channel , MRP , Adrenergic Receptor , ABC , Autophagy
	Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic ...
TP1992L	M40 acetate(143896-17-7 free base)		Neuropeptide Y Receptor
	M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates ...		Neuropeptide Y Receptor
T3173	DAA-1106	DAA1106	Others , GABA Receptor
	DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor.		Others , GABA Receptor
T21392	Flunarizine	Flunarizinum,Flunarizin,Sibelium,Flunarizina,R-14950
	Flunarizine is a non-selective calcium entry blocker and a histamine H1 receptor blocker. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, a...
T25102	Aprikalim	RP52891,RP-52891,RP 52891
	Aprikalim is a specific and selective ATP-sensitive K+ (KATP) channel opener. Aprikalim affords cardioprotection and at higher doses also cause peripheral or coronary vasodilatation.
T28335	PD 140376	PD-140376,PD140376
	PD 140376 is a highly selective antagonist radioligand for the cholecystokinin(B)-gastrin receptor in guinea pig gastric mucosa & cerebral cortex in the peripheral and central nervous systems.